Nanotraps for the containment and clearance of SARS-CoV-2
M. Chen, J. Rosenberg, X. Cai, A. C. H. Lee, J. Shi, M. Nguyen, T. Wignakumar, V. Mirle, A. J. Edobor, J. Fung, J. S. Donington, K. Shanmugarajah, E. B. Chang, G. Randall, P. Penaloza-MacMaster, , J. Huang
This paper introduces Nanotraps, functionalized nanoparticles that block SARS-CoV-2 infection by inhibiting spike protein-ACE2 interaction and triggering macrophage-mediated viral clearance.
bioRxiv · Feb 1, 2021Bioengineering