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T.-L. V. Lite

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Evolutionary Biology· 1

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Organism:bacteria (other)· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

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A. G. Green· 1 shared B. Wang· 1 shared D. Ding· 1 shared D. S. Marks· 1 shared E. N. Weinstein· 1 shared M. T. Laub· 1 shared

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A. G. Green

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Evolutionary BiologybioRxivPreprintOct 7, 2021

Coevolution of interacting proteins through non-contacting and non-specific mutations

D. Ding, A. G. Green, B. Wang…·M. T. Laub

The paper identifies enabling mutations in a bacterial toxin that tolerate antitoxin mutations, showing non-specific tolerance despite covariation primarily between contacting residues.

DOI 10.1101/2021.10.07.463098

bacteria (other)protein structure

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