BioengineeringbioRxivPreprint
Exploiting Index Cross-Talk to Modify Variant Calls
Peter M. Ney, Lee Organick, Karl Koscher…·Luis Ceze
The paper demonstrates how index cross-talk in DNA sequencing can be exploited to modify variant calls, showing a wild-type exome misclassified as heterozygous at the sickle-cell locus.
DOI 10.1101/332346