BioinformaticsGenome biologyPeer-reviewed
Distinguishing cells from empty droplets in droplet-based single-cell RNA sequencing data
Aaron T. L. Lun, Samantha J. Riesenfeld, Tallulah S. Andrews…·John C. Marioni
The paper introduces a statistical method to distinguish real cells from empty droplets in single-cell RNA sequencing data, improving detection of low-UMI cell libraries while controlling false discovery rates.
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