Author

Thomas A Johnson

National Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Andrew McGowan· 1 shared Blagoy BlagoeviD· 1 shared Chris DInzeo· 1 shared Daniel R. LarsoniD· 1 shared David A. BalliD· 1 shared Diana A. StavrevaiD· 1 shared Franck DequiedtiD· 1 shared Gianluca PegoraroiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andrew McGowan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Coordinated Temporal Dynamics of Glucocorticoid Receptor Binding and Chromatin Landscape Drive Transcriptional Regulation

Diana A. Stavreva, Sohyoung Kim, Saori Fujiwara, Andrew McGowan, Songjoon Baek, Lorenzo Rinaldi, Thomas A Johnson, Michele Puglia, Blagoy Blagoev, Franck Dequiedt, Gordon L. Hager, Grégory Fettweis

The paper defines a temporally resolved framework for GR-mediated gene regulation, identifying three binding classes and their functional links to transcriptional output.

bioRxiv · Apr 25, 2026 · PreprintMolecular Biology

Kinetic proofreading as a mechanism for transcriptional specificity in living human cells

Jee Min Kim, David A. Ball, Thomas A Johnson, Chris DInzeo, Hyeon Jin Cho, Laurent L. Ozbun, Tatiana Karpova, Gianluca Pegoraro, Daniel R. Larson

This study shows that transcriptional specificity is achieved through kinetic proofreading, where promoters discriminate specific TF interactions based on dwell time rather than occupancy.

bioRxiv · Mar 18, 2026 · PreprintBiophysics