Author

Laurent L. Ozbun

National Institutes of HealthORCID 0000-0002-0862-3929Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Gianluca PegoraroiD· 2 shared Tatiana KarpovaiD· 2 shared Adib KeikhosraviiD· 1 shared Chris DInzeo· 1 shared Daniel R. LarsoniD· 1 shared David A. BalliD· 1 shared Faisal AlmansouriD· 1 shared Hyeon Jin ChoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Gianluca PegoraroORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 9, 2026

Re-establishment of TAD boundary organization during DNA replication

Theodore Busby, Adib Keikhosravi, Mohamadreza Fazel…·Tom Misteli

The paper identifies DNA replication machinery components as critical for TAD boundary re-establishment during DNA replication.

DOI 10.64898/2026.07.08.737321

humanexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintMar 18, 2026

Kinetic proofreading as a mechanism for transcriptional specificity in living human cells

Jee Min Kim, David A. Ball, Thomas A Johnson…·Daniel R. Larson

This study shows that transcriptional specificity is achieved through kinetic proofreading, where promoters discriminate specific TF interactions based on dwell time rather than occupancy.

1 citation

𝕏 PostBluesky