Cancer BiologyEMBO Molecular MedicinePeer-reviewed
Primary cilia promote EMT-induced triple-negative breast tumor heterogeneity and resistance to therapy
Camille E. Tessier, Jennifer Derrien, Aurore M. M. Dupuy…·Vincent J. Guen
This study shows primary cilia in TNBC cells contribute to chemoresistance by supporting EMT-driven heterogeneity and stemness, and inhibiting ciliogenesis reduces this resistance.
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