Author

Tianyao Lu

The University of Melbourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:metabolomics· 3 Organism:human· 2 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

James Richard WhittleiD· 3 shared Sarah A. BestiD· 3 shared Saskia FreytagiD· 3 shared Vinod K. NarayanaiD· 3 shared Adam ValkoviciD· 2 shared Joel J D MoffetiD· 2 shared Jurgen KrieliD· 2 shared Malcolm John McConvilleiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersBioinformatics

James Richard WhittleORCID

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Author profile →

3 papers

Recent·Most cited

SpaMTP: Integrative Statistical Analysis and Visualisation of Spatial Metabolomics and Transcriptomics data.

Andrew Causer, Tianyao Lu, Jurgen Kriel, Joel J D Moffet, Christopher C. J. Fitzgerald, Andrew Newman, Hani Vu, Xiao Tan, Tuan Vo, Cedric S. Cui, Vinod K. Narayana, James Richard Whittle, Sarah A. Best, Saskia Freytag, Quan Hoang Nguyen

SpaMTP integrates spatial metabolomics and transcriptomics data through a comprehensive analysis pipeline and visualization tools.

Nature Methods · Jul 31, 2026Peer-reviewedBioinformatics

An integrative spatial multi-omic workflow for unified analysis of tumor tissue

Jurgen Kriel, Joel J D Moffet, Tianyao Lu, Ebenezer O. Fatunla, Vinod K. Narayana, Adam Valkovic, Ana C. Maluenda, Malcolm John McConville, Ellen Tsui, James Richard Whittle, Sarah A. Best, Saskia Freytag

This paper introduces a workflow for integrating spatial transcriptomics and metabolomics data to analyze glioma tissue, identifying novel biological features at the tumor's infiltrating edge.

Cell Reports Methods · Feb 1, 2026Peer-reviewedBioinformatics

Matrix selection for the visualization of small molecules and lipids in brain tumors using untargeted MALDI-TOF mass spectrometry imaging

Tianyao Lu, Lutz Freytag, Vinod K. Narayana, Zachery Moore, Shannon J. Oliver, Adam Valkovic, Brunda Nijagal, Amanda L. Peterson, David Peter De Souza, Malcolm John McConville, James Richard Whittle, Sarah A. Best, Saskia Freytag

The paper compares matrix, deposition technique, and polarity settings in MALDI-TOF mass spectrometry imaging for brain tumors, finding recrystallized cyano-4-hydroxycinnamic acid in positive polarity provides best performance.

Metabolites · Nov 9, 2023Peer-reviewedMolecular Biology