Author

Lutz Freytag

Walter and Eliza Hall Institute of Medical ResearchORCID 0009-0009-9256-6127Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

James Richard WhittleiD· 2 shared Sarah A. BestiD· 2 shared Saskia FreytagiD· 2 shared Tianyao Lu· 2 shared Vinod K. NarayanaiD· 2 shared Adam ValkoviciD· 1 shared Amanda L. PetersoniD· 1 shared Brunda NijagaliD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

James Richard WhittleORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Clinical InvestigationPeer-reviewedNov 19, 2024

Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition

Kristen E. Kay, Juyeun Lee, Ellen S. Hong…·Justin Durla Lathia

This study shows that spermidine, a metabolite from glioblastoma cells, suppresses CD8+ T cell function, promoting tumor growth and poor patient outcomes.

33 citationstop 3%

mousehuman

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Molecular BiologyMetabolitesPeer-reviewedNov 9, 2023

Matrix selection for the visualization of small molecules and lipids in brain tumors using untargeted MALDI-TOF mass spectrometry imaging

Tianyao Lu, Lutz Freytag, Vinod K. Narayana…·Saskia Freytag

The paper compares matrix, deposition technique, and polarity settings in MALDI-TOF mass spectrometry imaging for brain tumors, finding recrystallized cyano-4-hydroxycinnamic acid in positive polarity provides best performance.

18 citations

humanmouse

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