BioinformaticsbioRxivPreprint
Generative modeling reveals the connection between nuclear morphology and gene expression
Shuo Wen, Ramón Viñas, Johannes Bues…·Maria Brbić
COSMIC, a generative model, quantifies the relationship between nuclear morphology and gene expression using paired single-cell data, revealing morphology-associated genes in prostate cancer and spatial transcriptomics of zebrafish embryos.