NeuroscienceMethodsPeer-reviewed
A high-content imaging workflow to screen for molecules that reduce cellular uptake of α-synuclein preformed fibrils
Wolfgang Reintsch, Andrea I. Krahn, Chanshuai Han…·Thomas M. Durcan
The paper describes a high-content imaging assay to screen small molecules that reduce cellular uptake of α-synuclein preformed fibrils in hiPSC-derived cells, identifying compounds that effectively lower intracellular PFF load.