PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes
S. Singh, U. Dransfeld, Y. Ambaw, J. Lopez-Scarim, R. V. Farese, T. C. Walther
This study identifies PLD3 and PLD4 as enzymes synthesizing S,S-BMP, a lysosomal phospholipid critical for lipid degradation and brain health.
bioRxiv · Mar 21, 2024Biochemistry