Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer
A. Dondi, U. Lischetti, F. Jacob, F. Singer, N. Borgsmueller, R. Coelho, Tumor Profiler Consortium, V. Heinzelmann-Schwarz, C. Beisel, N. Beerenwinkel
This study uses long-read single-cell RNA sequencing to detect isoforms and genomic alterations in ovarian cancer, revealing novel isoforms, cell type-specific expression patterns, and gene fusions.
bioRxiv · Dec 12, 2022Cancer Biology