Author

A. Dondi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:long-read sequencing· 3 Assay:scRNA-seq· 3 Research Focus:variant calling· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

N. Beerenwinkel· 3 shared B. J. Haas· 2 shared F. Jacob· 2 shared Tumor Profiler Consortium· 2 shared V. Heinzelmann-Schwarz· 2 shared A. Castiglioni· 1 shared A. Davis· 1 shared A. Farfalla· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

N. Beerenwinkel

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Author profile →

4 papers

Recent·Most cited

De novo detection of somatic variants in high-quality long-read single-cell RNA sequencing data

A. Dondi, N. Borgsmüller, P. F. Ferreira, B. J. Haas, F. Jacob, V. Heinzelmann-Schwarz, Tumor Profiler Consortium, N. Beerenwinkel

LongSom detects somatic variants in LR scRNA-seq data without normal samples, revealing clonal heterogeneity in ovarian cancer.

bioRxiv · Mar 6, 2024Cancer Biology

CTAT-LR-fusion: accurate fusion transcript identification from long and short read isoform sequencing at bulk or single cell resolution

Q. Qin, V. Popic, H. Yu, E. White, A. Khorgade, A. Shin, K. Wienand, A. Dondi, N. Beerenwinkel, F. Vazquez, A. M. AlKhafaji, B. J. Haas

CTAT-LR-fusion detects fusion transcripts from long and short read RNA-seq data, improving accuracy in bulk and single cell transcriptomes.

bioRxiv · Feb 24, 2024Cancer Biology

NF1 modulates microtubule repair and sensitivity to antibody-drug conjugates

B. Achutti Duso, E. Messuti, G. Tini, E. Bonetti, A. Castiglioni, G. Frige, G. Ciossani, S. Monzani, C. Soriani, D. Khuntsariya, N. Roda, A. Polazzi, M. R. Ippolito, E. Gavilan Dorronzoro, E. Mane, , L. Mazzarella

This study shows that NF1 loss increases sensitivity to the ADC T-DM1 by modulating microtubule repair and dynamics, identifying NF1 as a predictive biomarker for ADC response.

bioRxiv · Dec 6, 2023 · PreprintCancer Biology

Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer

A. Dondi, U. Lischetti, F. Jacob, F. Singer, N. Borgsmueller, R. Coelho, Tumor Profiler Consortium, V. Heinzelmann-Schwarz, C. Beisel, N. Beerenwinkel

This study uses long-read single-cell RNA sequencing to detect isoforms and genomic alterations in ovarian cancer, revealing novel isoforms, cell type-specific expression patterns, and gene fusions.

bioRxiv · Dec 12, 2022Cancer Biology