Glucose intolerance in aging is mediated by the Gpcpd1-GPC metabolic axis
D. Cikes, M. Leutner, S. J. - F. Cronin, M. Novatchkova, L. Pfleger, R. Klepochova, E. Rullman, T. Gustafsson, A. Hagelkrueys, C. Knauf, C. Moro, M. Krebs, A. Kautzky-Willer, M. Krssak, M. Orthofer, , N. Viguerie
This study identifies Gpcpd1-GPC metabolic pathway perturbation in aging muscle as a driver of glucose intolerance.
bioRxiv · Oct 26, 2021 · PreprintPhysiology