Author

V. Corradi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electrophysiology· 1 Organism:human· 1

Frequent Co-Authors

D. P. Tieleman· 5 shared R.-X. Gu· 3 shared P. Vergani· 2 shared A. de La Cruz· 1 shared A. Golluscio· 1 shared A. Moussatova· 1 shared B. I. Sejdiu· 1 shared C. Degagne· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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5 shared papersBiophysics

D. P. Tieleman

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Author profile →

5 papers

Recent·Most cited

PUFA stabilizes a conductive state of the selectivity filter in IKs channels

A. Golluscio, J. Eldstrom, J. J. Jowais, M. E. Perez, K. P. Cunningham, A. de La Cruz, X. Wu, D. Fedida, P. Larsson, D. P. Tieleman, V. Corradi

This study investigates how PUFAs stabilize the selectivity filter of IKs channels, increasing their conductance and potentially treating Long QT Syndrome.

bioRxiv · Jan 11, 2024Biophysics

Can two wrongs make a right? F508del-CFTR ion channel rescue by second-site mutations in its transmembrane domains

S. Prins, V. Corradi, D. N. Sheppard, D. P. Tieleman, P. Vergani

This study identifies second-site mutations that rescue F508del-CFTR dysfunction by restoring hydrophobic interactions and conformational flexibility at the ICL4/NBD1 interface.

bioRxiv · Sep 7, 2021Biophysics

Structure of transmembrane helix 8 and possible membrane defects in CFTR

V. Corradi, R.-X. Gu, P. Vergani, D. P. Tieleman

This study uses molecular dynamics simulations to analyze the structural role of transmembrane helix 8 in CFTR and identifies a membrane defect specific to the ATP-free state.

bioRxiv · Nov 13, 2017Biochemistry

Lipid-Uptake Pathways and Lipid-Protein interactions in P-glycoprotein Revealed by Coarse-Grained Molecular Dynamics Simulations

E. Barreto-Ojeda, V. Corradi, R.-X. Gu, D. P. Tieleman

This study uses coarse-grained molecular dynamics simulations to identify lipid uptake pathways and interactions in P-glycoprotein, showing no selectivity between PC and PE lipids.

bioRxiv · Sep 20, 2017Biochemistry

Lipid-protein interactions are unique fingerprints for membrane proteins

V. Corradi, E. Mendez-Villuendas, H. Ingolfsson, R.-X. Gu, I. Siuda, M. N. Melo, A. Moussatova, C. Degagne, B. I. Sejdiu, G. Singh, T. Wassenaar, K. H. D. Magnero, S. J. Marrink, D. P. Tieleman

The paper uses molecular dynamics simulations to study lipid-protein interactions in membrane proteins, revealing unique lipid environments for each protein.

bioRxiv · Sep 20, 2017Biophysics