Author

V. Ferro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Khromykh· 2 shared D. Watterson· 2 shared M. Chhabra· 2 shared N. Modhiran· 2 shared A. A. Amarilla· 1 shared A. Amarilla· 1 shared A. Suhrbier· 1 shared C. E. Snell· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersImmunology

A. A. Khromykh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 triggers complement activation through interactions with heparan sulfate

M. W. Lo, A. A. Amarilla, J. D. Lee, E. A. Albornoz, N. Modhiran, R. J. Clark, V. Ferro, M. Chhabra, A. A. Khromykh, D. Watterson, T. M. Woodruff

This study shows SARS-CoV-2 activates the complement system via heparan sulfate interactions, leading to C5a production and delayed granulocyte/monocyte activation.

bioRxiv · Jan 11, 2022Immunology

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

S. E. Guimond, C. J. Mycroft-West, N. S. Gandhi, J. A. Tree, T. T. Le, C. M. Spalluto, M. V. Humbert, K. R. Buttigieg, N. Coombes, M. J. Elmore, K. Nystrom, J. Said, Y. X. Setoh, A. Amarilla, N. Modhiran, , J. E. Turnbull

This paper shows that pixatimod inhibits SARS-CoV-2 by disrupting the Spike-ACE2 interaction, demonstrating its potential as an anti-COVID-19 therapeutic.

bioRxiv · Jun 24, 2020Microbiology

Heparanase promotes Syndecan-1 expression to mediate fibrillar collagen and mammographic density in human breast tissue cultured ex vivo.

X. Huang, G. Reye, K. I. Momot, T. Blick, T. Lloyd, W. D. Tilley, T. E. Hickey, C. E. Snell, R. K. Okolicsanyi, L. M. Haupt, V. Ferro, E. W. Thompson, H. J. Hugo

bioRxiv · Jun 4, 2020Cancer Biology