ImmunologybioRxiv
SARS-CoV-2 triggers complement activation through interactions with heparan sulfate
M. W. Lo, A. A. Amarilla, J. D. Lee…·T. M. Woodruff
This study shows SARS-CoV-2 activates the complement system via heparan sulfate interactions, leading to C5a production and delayed granulocyte/monocyte activation.
DOI 10.1002/cti2.1413