Adaptation to host cell environment during experimental evolution of Zika virus
V. Grass, E. Hardy, K. Kobert, S. R. Talemi, E. Decembre, C. Guy, P. V. Markov, A. Kohl, M. Paris, A. Böckmann, S. Munoz-Gonzalez, L. Sherry, T. Höfer, B. Boussau, M. Dreux
This study identifies genetic adaptations in Zika virus during experimental evolution in host cells, revealing increased infectivity and resistance to TLR3-induced restriction.
bioRxiv · Dec 28, 2020Microbiology