BiochemistrybioRxiv
The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleotide selectivity of PNPs
J. Torini, L. Romanello, F. Batista…·H. Pereira
This paper characterizes the structural and kinetic properties of SmPNP2, a new PNP isoform from Schistosoma mansoni, revealing its ability to bind and catalyze both pyrimidines and purines with a unique binding mode.
DOI 10.1371/journal.pone.0203532