Author

V. Kunetsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

P. Friedhoff· 2 shared A. Borsellini· 1 shared C. Laffeber· 1 shared G. Brouwer· 1 shared J. Lebbink· 1 shared M. H. Lamers· 1 shared M. S. Dillingham· 1 shared O. Storozhuk· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

P. Friedhoff

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2 papers

Recent·Most cited

DNA mismatch and damage detection using a FRET-based assay for monitoring the loading of multiple MutS sliding clamps

V. Kunetsky, O. Storozhuk, G. Brouwer, C. Laffeber, M. S. Dillingham, J. Lebbink, P. Friedhoff

The paper develops a FRET-based assay using MutS to detect DNA mismatches and damage by monitoring ATP-dependent loading of multiple MutS sliding clamps.

bioRxiv · Jul 23, 2021 · PreprintBiochemistry

Cryo-EM structures reveal how ATP and DNA binding in MutS coordinate the sequential steps of DNA mismatch repair

A. Borsellini, V. Kunetsky, P. Friedhoff, M. H. Lamers

The paper presents cryo-EM structures of Escherichia coli MutS at different stages of the ATP hydrolysis cycle, revealing how ATP binding and hydrolysis induce conformational changes that coordinate DNA mismatch repair.

bioRxiv · Jun 3, 2021Biochemistry