BioE3 enables the identification of bona fide targets of E3 ligases
O. Barroso-Gomila, L. Merino-Cacho, V. Muratore, C. Perez, V. Taibi, E. Maspero, M. Azkargorta, I. Iloro, F. Trulsson, A. C. O. Vertegaal, U. Mayor, F. Elortza, S. Polo, R. Barrio, J. D. Sutherland
BioE3 identifies substrates of UbL E3 ligases by site-specific biotinylation and proteomic analysis, revealing both known and novel targets for various E3 ligases.
bioRxiv · Aug 18, 2023Cell Biology