A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation
M. W. Bahar, V. Nasta, H. Fox, L. Sherry, K. Grehan, C. Porta, A. J. Macadam, N. J. Stonehouse, D. J. Rowlands, E. E. Fry, D. I. Stuart
This study identifies a conserved glutathione binding site in poliovirus VLPs that can be targeted by antivirals and used to stabilize vaccines.
bioRxiv · Sep 8, 2022Biochemistry