Author

V. Siebert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

M. K. Lemberg· 2 shared A. J. O'Donoghue· 1 shared C. Muhle-Goll· 1 shared E. Arutyunova· 1 shared E. Heuten· 1 shared E. Takyi· 1 shared H. S. Young· 1 shared L. Lysyk· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

M. K. Lemberg

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cleavage of PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state

V. Siebert, M. Silber, E. Heuten, C. Muhle-Goll, M. K. Lemberg

This study identifies key residues and structural features in PGAM5 that determine its cleavage by PARL, showing that membrane potential uncoupling affects its oligomeric state and processing.

bioRxiv · Nov 19, 2021 · PreprintCell Biology

Insights into the catalytic properties of the mitochondrial rhomboid protease PARL

L. Lysyk, R. Brassard, E. Arutyunova, V. Siebert, Z. Jiang, E. Takyi, M. Morrison, H. S. Young, M. K. Lemberg, A. J. O'Donoghue, M. J. Lemieux

This study investigates the catalytic properties of the mitochondrial rhomboid protease PARL using in vitro assays, revealing substrate preferences and activity enhancements under specific conditions.

bioRxiv · Jul 27, 2020Biochemistry