Author

V. Sriram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Blanckaert· 1 shared C. A. Castellanos· 1 shared C. Bank· 1 shared C. Beppler· 1 shared E. Cai· 1 shared J. Eichorst· 1 shared K. Marchuk· 1 shared K. T. Roybal· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperEvolutionary Biology

A. Blanckaert

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Author profile →

2 papers

Recent·Most cited

In search of the Goldilocks zone for hybrid speciation II: hard times for hybrid speciation?

A. Blanckaert, V. Sriram, C. Bank

The paper models how population size, linkage architecture, and incompatibility strength affect hybrid speciation and extinction risk in hybrid populations.

bioRxiv · Feb 15, 2023Evolutionary Biology

Visualizing and manipulating hyperstabilization of T cell microvilli contacts by engineered chimeric antigen receptors

C. Beppler, J. Eichorst, K. Marchuk, E. Cai, C. A. Castellanos, V. Sriram, K. T. Roybal, M. F. Krummel

This study uses advanced imaging to show that engineered CARs with high affinity hyperstabilize T cell microvilli contacts, impairing function, while reducing affinity restores normal dynamics and improves effector function.

bioRxiv · Aug 18, 2021Immunology