Cross-species comparison reveals therapeutic vulnerabilities halting glioblastoma progression
L. C. Foerster, O. Kaya, V. Wust, D.-P. Danciu, M. Bekavac, K. C. Ziegler, V. Akcay, N. Stinchcombe, A. Tang, J. Tang, J. Brunken, N. Gesteira Perez, X. Ma, A. Sadik, C. Opitz, , A. Martin-Villalba
This study identifies SFRP1 as a therapeutic target for glioblastoma by revealing its role in reprogramming tumor methylomes and improving survival in mouse models.
bioRxiv · Sep 15, 2023Cancer Biology