Author

Valentin Garcia

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Hélène HirbeciD· 3 shared François Rassendren· 2 shared Alexandre BénaniiD· 1 shared Alexandre LucasiD· 1 shared Alexis‐Pierre BemelmansiD· 1 shared Anaïs VignoniD· 1 shared Anne-Laure Hemonnot-GirardiD· 1 shared Arnaud PolizziiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Hélène HirbecORCID

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3 papers

Recent·Most cited

Postprandial hypertriglyceridemia activates microglia to promote satiety via an ASC dependent signaling.

Juliette Salvi, Emmanuelle Nédélec, Lucie Leret, Fabienne Liénard, Tatiana Landré, Selma Ben Fradj, Valentin Garcia, Vincent Gigot, Bruno Patris, Vivien Pires, Arnaud Polizzi, Clara Sanchez, Thomas Gautier, Hervé Guillou, Tony Heurtaux, , Alexandre Bénani

This study shows that postprandial hypertriglyceridemia activates microglia to promote satiety via an ASC-dependent signaling pathway, which is sexually dimorphic and disrupted in obesity.

bioRxiv · Oct 13, 2026 · PreprintNeuroscience

Local translation controls early reactive changes in perisynaptic astrocyte processes at pre-symptomatic stages of Alzheimers disease

Katia Avila‐Gutierrez, María-Angeles Carrillo-de Sauvage, Noémie Depret, Marc Oudart, Robin Thompson, Rodrigo Alvear‐Perez, Yiannis Poulot-Becq-Giraudon, Esther Kozlowski, Héloïse Monnet, Philippe Mailly, Valentin Garcia, Laurent Jourdren, Alexandre Lucas, Alexis‐Pierre Bemelmans, Hélène Hirbec, , Martine Cohen‐Salmon

The paper identifies astrocyte perisynaptic processes as sites of early translational dysregulation in Alzheimer's disease, linking it to synaptic dysfunction and disease initiation.

Neurobiology of Disease · Jul 9, 2026Peer-reviewedNeuroscience

APPNL-F knock-in Alzheimer's Disease model mice reveal etiological convergence of aging and amyloidosis

Matthieu Prieur, Anne-Laure Hemonnot-Girard, Valentin Beck, Valentin Garcia, Thanawat Phuadraksa, Nathalie Linck, Manon Leportier, Anaïs Vignon, Dany Séverac, Véronique Perrier, François Rassendren, Marc Dhénain, Takashi Saito, Takaomi C. Saido, Hélène Hirbec

This study characterizes the early stages of amyloidosis and neuroinflammation in APPNL-F AD model mice, revealing a link between microglial senescence and disease progression.

bioRxiv · Jan 31, 2026 · PreprintNeuroscience