Thomas Gautier

This study shows that postprandial hypertriglyceridemia activates microglia to promote satiety via an ASC-dependent signaling pathway, which is sexually dimorphic and disrupted in obesity.

This study shows that atheroma plaque microenvironment activates the kynurenine pathway in macrophages, increasing kynurenine production which induces endothelial adhesion molecules, promoting atherogenesis.