Author

Valentina Leone

Technical University of Munich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Maximilian ReichertiD· 2 shared Alba Schmahl Fernandez· 1 shared Amirhossein SakhtemaniD· 1 shared Andrea SchmidtsiD· 1 shared Andreas CarriD· 1 shared Bernhard KüsteriD· 1 shared Daniela Abele· 1 shared Dirk Hans BuschiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Maximilian ReichertORCID

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2 papers

Recent·Most cited

Cancer BiologyMolecular Systems BiologyPeer-reviewedJan 21, 2025

Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response

Stefanie Höfer, Larissa Frasch, Sarah Brajkovic…·Bernhard Küster

This study identifies ATR inhibitors as synergistic with gemcitabine in killing PDAC cells by blocking the DNA damage response pathway.

31 citationstop 1%

humanproteomics

𝕏 PostBluesky

BioengineeringbioRxivPreprintNov 25, 2024

Engineering de novo binder CAR-T cell therapies with generative AI

Markus Mergen, Daniela Abele, Naile Koleci…·Andrea Schmidts

This paper demonstrates the use of generative AI to design de novo binders for CAR-T cells targeting cancer antigens, showing comparable efficacy to traditional scFv-based CAR-T cells.

10 citations

humanproteomics

𝕏 PostBluesky