Pathobiology of the autophagy-lysosomal pathway in the Huntington's disease brain
M. J. Berg, Veeranna, C. M. Rosa, A. Kumar, P. S. Mohan, P. Stavrides, D. M. Marchionini, D.-S. Yang, R. A. Nixon
This study investigates the role of the autophagy-lysosomal pathway in Huntington's disease, finding that autophagic flux declines due to substrate clearance deficits in later stages.
bioRxiv · May 29, 2024 · PreprintPathology