Author

D.-S. Yang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

D. M. Marchionini· 2 shared P. Stavrides· 2 shared R. A. Nixon· 2 shared A. C. Bartnik· 1 shared A. Kumar· 1 shared A. W. P. Fitzpatrick· 1 shared C. Huo· 1 shared C. J. R. Duncan· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersPathology

D. M. Marchionini

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Author profile →

3 papers

Recent·Most cited

mTOR inhibition in Q175 Huntington's disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

P. Stavrides, C. N. Goulbourne, J. Peddy, C. Huo, M. Rao, V. Khetarpal, D. M. Marchionini, R. A. Nixon, D.-S. Yang

This study shows that mTOR inhibition in HD model mice improves autophagy and reduces mutant huntingtin accumulation.

eLife · May 20, 2025Peer-reviewedPathology

Pathobiology of the autophagy-lysosomal pathway in the Huntington's disease brain

M. J. Berg, Veeranna, C. M. Rosa, A. Kumar, P. S. Mohan, P. Stavrides, D. M. Marchionini, D.-S. Yang, R. A. Nixon

This study investigates the role of the autophagy-lysosomal pathway in Huntington's disease, finding that autophagic flux declines due to substrate clearance deficits in later stages.

bioRxiv · May 29, 2024 · PreprintPathology

Development of an ultrafast pulsed ponderomotive phase plate for cryo-electron tomography

D. X. Du, A. C. Bartnik, C. J. R. Duncan, U. Choudhry, T. Tabachnik, C. Sallah, E. Najafi, D.-S. Yang, J. M. Maxson, A. W. P. Fitzpatrick

This paper develops an ultrafast pulsed ponderomotive phase plate to enhance contrast in cryo-ET by synchronizing electron packets with laser pulses.

bioRxiv · Mar 20, 2024 · PreprintBiophysics