Cell BiologybioRxivPreprint
Requirement of FLCN tumor suppressor gene for mTORC1-mediated inhibition of TFE3 transcriptional activity
Hua Li, HyoungBin Oh, Benoit Viollet…·Seung-Beom Hong
This study shows that FLCN is required for mTORC1-mediated inhibition of TFE3 activity, which regulates lysosomal gene expression under metabolic stress.
DOI 10.1101/2020.07.08.193169