Author

Vibha Vasireddy

University of Washington

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Biochemistry· 1

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1

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A G MurrayiD· 1 shared Alex KangiD· 1 shared Alexandria N. LeveilleiD· 1 shared Alina ÜffingiD· 1 shared Andi LiuiD· 1 shared Asim K. BeraiD· 1 shared David A. BakeriD· 1 shared David JuergensiD· 1 shared

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1 shared paperBiochemistry

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1 paper

Recent·Most cited

BiochemistryNature Chemical BiologyPeer-reviewedJun 20, 2025

Accurate de novo design of high-affinity protein binding macrocycles using deep learning

Stephen Rettie, David Juergens, Victor Adebomi…·Gaurav Bhardwaj

This paper introduces RFpeptides, a deep learning framework for designing high-affinity macrocyclic peptides, achieving sub-nanomolar binding affinities and accurate structural predictions.

114 citationstop 1%

protein structuredeep learning

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