Refractive index modulation by ultraviolet absorption of canonical amino acids for in vivo optical transparency
Su Zhao, Zhongyu Liu, Ling-Yi Zhang, Xuandi Hou, Ani Baghdasaryan, Han Cui, Victoria Crunkleton, Carl H. C. Keck, Dominic Myung, Tianming M Yang, Kerriann M. Casey, Patrice M. Witschen, Guosong Hong
This study identifies arginine as a key amino acid for achieving optical transparency in tissues through its ultraviolet absorption and refractive index modulation properties.
bioRxiv · Aug 26, 2026 · PreprintBiophysics