Molecular BiologybioRxiv
Fork Pausing Complex Engages Topoisomerases at the Replisome
Maksym Shyian, Benjamin Albert, Andreja Moset Zupan…·David Shore
The paper shows that the Tof1-Csm3 complex recruits topoisomerase I to the replisome to promote fork pausing at replication fork barriers, independent of Rrm3 helicase.
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