Deprivation of dietary fiber promotes low-grade neuroinflammation and anxiety-like behavior in mice
Adewale Oyetunde, Dhanya N Pyaram, Vu Ngo, Chao Li, Hirohito Abo, Jun Zou, Angela M Mabb, Andrew T Gewirtz
This study shows that depriving mice of fermentable dietary fiber leads to low-grade neuroinflammation and anxiety-like behavior, which are reversed by fiber supplementation.
bioRxiv · Nov 6, 2026 · PreprintNeuroscience