Differences in Activation of Intracellular Signalling in Primary Human Retinal Endothelial Cells Between Isoforms of VEGFA-165.
W. Dailey, R. Schunemann, F. Yang, M. Moore, A. Knapp, P. Chen, M. Deshpande, B. Metcalf, Q. Tompkins, A. E. Guzman, J. Felisky, K. P. Mitton
This study compares the activation of MAPK and AKT signaling pathways by VEGFA165a and VEGFA165b in primary human retinal endothelial cells, finding stronger activation by VEGFA165a at lower doses.
bioRxiv · Dec 12, 2019 · PreprintCell Biology