Hsp22 is the key sensor and balancer in mitochondrial dynamic associated metabolic reprogramming
W. Zaiwa, C. Ying, W. Xueyi, W. Wenjing, T. Ning, S. Fang, T. Yafang, M. Jingxin, L. Rujia, P. Tianchan, H. Yanmei, Z. Quan, W. Lili, L. Liangxian, W. Xiaoli, L. Qinghua
The paper shows that Hsp22 overexpression reverses metabolic reprogramming and pathogenic phenotypes in tumor and Parkinson's disease models by restoring mitochondrial homeostasis.
bioRxiv · Nov 22, 2020 · PreprintCancer Biology