Single-molecule analysis reveals the role of regulatory light chains in fine-tuning skeletal myosin-II function
A. Nayak, T. Wang, P. Franz, W. Steffen, I. Chizhov, G. Tsiavaliaris, M. Amrute-Nayak
The paper investigates how regulatory light chains (RLCs) influence the functional diversity of myosin-II isoforms by swapping RLCs with different myosin heavy chains and measuring changes in actin filament sliding velocity.
bioRxiv · Jan 21, 2020Biophysics