Tongue immune compartment analysis reveals spatial macrophage heterogeneity
A. Mildner, E. M. Lyras, K. Zimmermann, L. K. Wagner, D. Dörr, C. Fischer, S. Jung, S. Yona, A.-H. Hovav, W. Stenzel, S. Dommerich, T. Conrad, A. Leutz
This study identifies two distinct macrophage subsets in the murine tongue using single-cell RNA-sequencing and in situ immunophenotyping, revealing their spatial distribution and differential responses to systemic LPS.
bioRxiv · Feb 9, 2022Immunology