Epicardial reservoir-enabled multidose delivery of exogenous FSTL1 leads to improved cardiac function, healing, and angiogenesis.
C. E. Varela, D. S. Monahan, S. Islam, W. Whyte, J. Bonnemain, S. Ngoy, S. Fisch, G. P. Duffy, E. T. Roche
This study investigates the effects of multidose FSTL1 delivery via an epicardial reservoir in a rat MI model, finding improved cardiac function, healing, and angiogenesis with increasing doses.
bioRxiv · Nov 2, 2022 · PreprintBioengineering