Author

W.-C. Chou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Rao· 1 shared C. Blouin· 1 shared C.-Y. Shen· 1 shared G. J. Faulkner· 1 shared H. Sepulveda· 1 shared H.-F. Tien· 1 shared J. Fernandez· 1 shared L. J. A. Vazquez· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Rao

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Author profile →

2 papers

Recent·Most cited

A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia

Z. Dong, H. Sepulveda, L. J. A. Vazquez, C. Blouin, J. Fernandez, M. Binder, W.-C. Chou, H.-F. Tien, G. J. Faulkner, S. A. Myers, M. Patnaik, A. Rao

This study shows that mutant ASXL1 proteins disrupt heterochromatin integrity in clonal hematopoiesis and CMML by reducing H3K9me2/3 and H2AK119Ub, leading to increased transposable element expression.

bioRxiv · Jan 30, 2024 · PreprintCancer Biology

Analysis of single-cell RNA-sequencing data to identify quiescent and proliferating neural cell populations in Glioblastoma

R. Vikram, W.-C. Chou, P.-E. Wu, W.-T. Chen, C.-Y. Shen

This study identifies gene signatures associated with quiescent and proliferating neural cell populations in glioblastoma using single-cell RNA-sequencing data from multiple studies.

bioRxiv · Dec 9, 2021 · PreprintCancer Biology