Uremic toxin indoxyl sulfate induces trained immunity via the AhR-dependent arachidonic acid pathway in end-stage renal disease (ESRD)
H. Y. Kim, Y. J. Kang, D. H. Kim, J. Jang, S. J. Lee, G. Kim, H. B. Koh, Y. E. Ko, H. M. Shin, H. Lee, T.-H. Yoo, W.-W. Lee
This study shows indoxyl sulfate induces trained immunity in monocytes via AhR-dependent arachidonic acid pathway, contributing to inflammation in ESRD.
bioRxiv · Aug 8, 2022Immunology