G. Kim

Light-Controlled Synthetic Communication Networks via Paired Connexon Nanopores

The paper demonstrates wavelength-dependent communication between synthetic cells using engineered connexin channels that respond to UV and near IR light.

Pools of independently cycling inositol phosphates revealed by pulse labeling with 18O-water

The paper uses 18O-water labeling to study phosphate group dynamics in inositol phosphates across species, revealing distinct pools with different cycling behaviors.

Stimulative piezoelectric nanofibrous scaffolds for enhanced small extracellular vesicle production in 3D cultures

This paper develops a 3D culture platform using piezoelectric nanofibrous scaffolds with acoustic stimulation to significantly enhance small extracellular vesicle production.

Spatially resolved niche and tumor microenvironmental alterations in gastric cancer peritoneal metastases

This study identifies transcriptomic and immune features of gastric cancer peritoneal metastases, highlighting predictive markers and therapeutic targets in the tumor microenvironment.

Single cell view of tumor microenvironment gradients in pleural mesothelioma

This paper uses single-cell RNA-sequencing to analyze the tumor microenvironment in pleural mesothelioma, identifying gene programs, fetal-like endothelial cells, and a new therapeutic target.

Modeling Neuromotor Adaptation to Pulsed Torque Assistance During Walking

This paper validates existing models of motor learning in gait training and proposes a modified use-dependent learning model that achieves better fit with fewer parameters.

High-resolution low-cost LCD 3D printing of microfluidics

This paper introduces low-cost LCD 3D printing for microfluidic device fabrication using a tailored ink, achieving high resolution and compatibility with cell culture.

Fluorescent Chiral Quantum Dots to Unveil Origin-Dependent Exosome Uptake and Cargo Release

This study uses chiral quantum dots to investigate origin-dependent exosome uptake and cargo release mechanisms in different recipient cells.

Revealing 3D cancer tissue structures using holotomography and virtual hematoxylin and eosin staining via deep learning

This paper develops a 3D virtual H&E staining method using holotomography and deep learning for cancer tissues, validated on colon and gastric cancer samples.

Intronic miR342 is a master regulator of cellular glycolysis in Foxp3+ regulatory CD4 T cells

This study identifies miR-342 as a master regulator of glycolysis in Foxp3+ regulatory T cells, essential for controlling inflammation in the central nervous system.

Functional immune state classification of unlabeled live human monocytes using holotomography and machine learning

This study uses holotomography and machine learning to classify functional immune states of human monocytes, achieving high accuracy in identifying hyper-inflammatory and immune-suppressed states.

Enhanced functionalities of immune cells separated by microfludic lattice: assessment based on holotomography

This study compares microfluidic and centrifugation methods for isolating white blood cells, finding microfluidic separation better preserves cell functionality.

Chirality-Enhanced Transport and Drug Delivery of Graphene Nanocarriers to Tumor-like Cellular Spheroid

This study shows that left-handed graphene quantum dots (L-GQDs) have higher diffusion and drug delivery efficacy in tumor-like spheroids compared to right-handed D-GQDs.

Label-free histological analysis of retrieved thrombi in acute ischemic stroke using optical diffraction tomography and deep learning

This study uses optical diffraction tomography and deep learning to automate thrombus composition analysis in acute ischemic stroke, achieving high accuracy and reducing labor.

Inositol pyrophosphate dynamics reveals control of the yeast PHO starvation program through 1,5-IP8 and the SPX domain of Pho81

The paper shows that 1,5-IP8 decline triggers the yeast PHO starvation response by inactivating Pho81 through its SPX domain, revealing a unified model of phosphate signaling across eukaryotes.

Lymphocyte activation gene 3 (Lag3) supports Foxp3+ Treg cell function by restraining c-Myc-dependent aerobic glycolysis

This study shows Lag3 supports Foxp3+ Treg cell function by restraining c-Myc-dependent aerobic glycolysis, which is critical for suppressing autoimmune inflammation.

Chiral Graphene Quantum Dots Enhanced Drug Loading into Exosomes

This paper presents a chiral graphene quantum dots platform for efficient drug loading into exosomes, achieving high loading efficiencies for both hydrophobic and hydrophilic drugs.

Structural insights into ubiquitin chain cleavage by Legionella ovarian tumor deubiquitinases

This study reveals the structural features and mechanism of Legionella OTU deubiquitinases, showing their unique extended helical lobe and cooperative chain cleavage activity.

Metabolic consequences of polyphosphate synthesis and imminent phosphate limitation

This study investigates how polyphosphate synthesis and phosphate limitation affect yeast metabolism, revealing that polyphosphate serves metabolic roles beyond phosphate storage.

Triangulation reduces the polygon of error for the history of Transeurasian

The paper addresses critiques of a Transeurasian language and population history study by revising datasets and methods, showing that the original findings remain valid despite objections.

Uremic toxin indoxyl sulfate induces trained immunity via the AhR-dependent arachidonic acid pathway in end-stage renal disease (ESRD)

This study shows indoxyl sulfate induces trained immunity in monocytes via AhR-dependent arachidonic acid pathway, contributing to inflammation in ESRD.

Long-term label-free assessments of individual bacteria using three-dimensional quantitative phase imaging and hydrogel-based immobilization

This paper introduces a hydrogel-based method for long-term label-free 3D imaging of live bacteria, enabling precise analysis of biophysical parameters and antibiotic responses.

Topology of gene regulatory compartments relative to the nuclear matrix

The paper visualizes the nuclear matrix and intranuclear compartments using super-resolution microscopy, revealing their layered distribution and role in transcriptional regulation.

Systematic Characterization of Double Emulsion Droplets for Biological Applications

This paper systematically characterizes double emulsion droplets to predict their size and stability based on flow rates and buffer properties, enabling better design of bioassays.

Poly(A)-binding protein is an ataxin-2 chaperone that emulsifies biomolecular condensates.

The paper identifies a conserved 14aa sequence in ataxin-2 that acts as a condensation switch and reveals poly(A)-binding proteins as RNA-dependent chaperones that regulate this switch.

Rapid label-free identification of pathogenic bacteria species from a minute quantity 1 exploiting three-dimensional quantitative phase imaging and artificial neural network

This paper develops a framework for rapid bacterial species identification using 3D quantitative phase imaging and artificial neural networks, achieving 99.9% accuracy with single colony-forming units.

Dendrimer-like supramolecular assembly of proteins with a tunable size and valency through stepwise iterative growth

This paper introduces a programmable method to create tunable, multi-valent protein assemblies called prodrimers, showing enhanced binding affinity and cytotoxicity.

Using Bayesian Optimization to Identify Optimal Exoskeleton Parameters Targeting Propulsion Mechanics: A Simulation Study

This study uses Bayesian optimization to simulate human-in-the-loop experiments for optimizing exoskeleton parameters based on propulsion mechanics, finding expected improvement as the most effective acquisition method.

Live imaging of breast tumors shows macrophage-dependent induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination

The paper uses intravital imaging to show macrophage-induced cancer stem cells (CSCs) are enriched at TMEM doorways during metastasis, with CSCs comprising >60% of circulating tumor cells.

Data-driven multiplexed microtomography of endogenous subcellular dynamics

This paper introduces a data-driven method for multiplexed microtomography using refractive index imaging to study endogenous subcellular dynamics without exogenous labels.