A new concept in antiviral drug design yields a potent influenza inhibitor
C. Mackenzie-Kludas, W.-Y. Wu, B. Jin, J. L. McKimm-Breschkin, E. L. Seah, P. Jones, E. Fairmaid, C. M. K. Tai, D. Y. Oh, P. Jenkins, A. C. Hurt, L. E. Brown
This paper introduces a new antiviral drug design approach that alters the virion surface microenvironment to block influenza virus entry, showing potent in vitro and in vivo activity.
bioRxiv · Nov 8, 2022 · PreprintMicrobiology