B. Jin

ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia

This study uses scRNA-seq and scATAC-seq to identify stage-specific interactions between Sertoli cell subtypes and germ cells in NOA, revealing potential molecular markers for diagnostic kits.

Electron-bifurcation and fluoride efflux systems in Acetobacterium spp. drive defluorination of perfluorinated unsaturated carboxylic acids

This study identifies electron-bifurcation and fluoride efflux systems in Acetobacterium spp. that enable reductive defluorination of PFAS, supported by biochemical and structural evidence.

SCFFBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation.

The paper identifies FBXW11 as a ubiquitin ligase that targets IL-17RA for proteasomal degradation through lysine 27-linked polyubiquitin chains.

Directing polymorph specific calcium carbonate formation with de novo protein templates

De novo designed protein templates promote nucleation of nano-calcite and direct its growth by oriented particle attachment.

Anionic Phospholipids Control Mechanisms of GPCR-G Protein Recognition

This study shows anionic lipids facilitate GPCR-G protein complex formation through conformational selection, with computational models supporting charge complementarity as a general mechanism.

A new concept in antiviral drug design yields a potent influenza inhibitor

This paper introduces a new antiviral drug design approach that alters the virion surface microenvironment to block influenza virus entry, showing potent in vitro and in vivo activity.

COEVOLUTION WITH SPATIALLY STRUCTURED RICE LANDRACES MAINTAINS MULTIPLE GENERALIST LINEAGES IN THE RICE BLAST PATHOGEN

The paper examines the coevolution between rice landraces and their blast pathogen in China, finding that generalist pathogen lineages coexist with host genetic subdivision.

CHIQUITA1 maintains temporal transition between proliferation and differentiation in Arabidopsis thaliana

This study identifies CHIQUITA1 as a gene required to maintain the timing of the transition from proliferation to differentiation in Arabidopsis thaliana, influencing organ size.

IFITM3 regulates virus-induced inflammatory cytokine production by titrating Nogo-B orchestration of TLR responses

This study shows IFITM3 limits viral pathogenesis by regulating Nogo-B-mediated TLR responses and cytokine production in dendritic cells.

A Bivalent Chromatin Controls Timing of Expression of Camalexin Biosynthesis Genes in Response to a Pathogen Signal in Arabidopsis

The paper identifies a bivalent chromatin state, called a kairostat, that controls the timing of camalexin biosynthesis gene expression in Arabidopsis in response to pathogen signals.

The jasmine (Jasminum sambac) genome and flower fragrances

This study presents the first de novo genome of Jasminum sambac and identifies gene clusters and pathways involved in flower fragrance biosynthesis.

Divergent selection on behavioral and chemical traits contributes to isolation between populations of Drosophila melanogaster

The paper investigates how divergent sexual selection on male courtship and cuticular hydrocarbons contributes to reproductive isolation in Drosophila melanogaster.

Hydration-dependent phase separation of a prion-like protein regulates seed germination during water stress.

This study identifies FLOE1, a prion-like protein in Arabidopsis thaliana, whose hydration-dependent phase separation regulates seed germination under water stress.

Low basal expression and slow induction of IFITM3 puts immune cells at risk of influenza A infection

This study shows that low basal expression and slow induction of IFITM3 in immune cells increases their susceptibility to influenza A virus infection.

3D computational models explain muscle activation patterns and energetic functions of internal structures in fish swimming

This study uses 3D computational fluid dynamics to explain muscle activation patterns and energy dynamics in fish swimming, revealing how torque, power, and body elasticity contribute to different swimming modes.