Author

Wei Wu

Army Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 2 Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Approach:diffusion model· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alessandro Pinto· 1 shared Aziz FarhatiD· 1 shared Bonnie WangiD· 1 shared Chen Li· 1 shared Cheng ZhangiD· 1 shared Chi-Jung Chung· 1 shared David Yu ZhangiD· 1 shared Dong-En Lee· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBioengineering

Alessandro Pinto

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4 papers

Recent·Most cited

Metabolite-centric Knowledge Graph Unveils Predictive and Mechanistic Insights through Self-supervised Multimodal Learning

Yuxing Lu, Xinru Guan, Wei Wu, Li Quan, Lin Wang, Chen Li, Jinzhuo Wang

This paper introduces MetaKG, a metabolite-centric knowledge graph with self-supervised learning that improves representation learning and uncovers biochemical relationships.

bioRxiv · Oct 19, 2026 · PreprintBioinformatics

Scaling Multiplex qPCR Primer Design to 1000-plex using the Degenerate Incomplete Multiplex Primer List Extension (DIMPLE) Algorithm

Alessandro Pinto, Xue Dong, Wei Wu, Sara J. Johnson, Qin Wen, Cheng Zhang, Jana Havey, Bonnie Wang, Guilin Tang, Aziz Farhat, David Yu Zhang, Ghayas C. Issa, Xi Zhang

The paper introduces DIMPLE, a scalable qPCR primer design algorithm that enables 10,000+ primers in a single reaction, achieving low VAF detection and multiplex applications.

bioRxiv · Apr 21, 2026 · PreprintBioengineering

Analysis of crosslinking sites suggests C. elegnas PIWI Argonaute exhibits flexible conformations for target recognition

Wei Wu, Dong-En Lee, Chi-Jung Chung, Shang-Yi Lu, Jordan S. Brown, Donglei Zhang, Heng-Chi Lee

The paper develops MUTACLASH to analyze CIMs in CLASH data, revealing that CIMs are enriched at piRNA/miRNA target sites and suggest flexible conformations of PRG-1 for target recognition.

bioRxiv · Feb 14, 2025 · PreprintMolecular Biology

LRTM: Left-Right Transition Matrices for Molecular Interaction Prediction

Kai Zheng, Guihua Duan, Mengyun Yang, Wei Wu, Yao-Hang Li, Jianxin Wang

This paper introduces LRTM, a method for molecular interaction prediction using transition matrices, showing improved performance and cross-task potential.

bioRxiv · Feb 6, 2025 · PreprintBioinformatics