Author

Chen Li

Beijing Ming Vision and Ophthalmology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Immunology· 1 Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alison C. LivadaiD· 1 shared Annabel M.J. Adams· 1 shared Baoming Zhong· 1 shared Brian J. LeeiD· 1 shared Craig N. MorrelliD· 1 shared Daniel P. O’ReillyiD· 1 shared Dingwen Zhang· 1 shared Ei Thanda TuniD· 1 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperImmunology

Alison C. LivadaORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

Failed allogeneic corneal lenticules show fibrosis and identity loss without dominant T cell rejection

Hanyu Jiang, Yu Di, Chen Li, Yang Jiang, Ying Li, Yuehua Zhou

The paper examines failed allogeneic corneal lenticules, finding fibrosis and loss of corneal identity without dominant T cell rejection, and explores treatment strategies.

bioRxiv · Nov 5, 2026 · PreprintPathology

Metabolite-centric Knowledge Graph Unveils Predictive and Mechanistic Insights through Self-supervised Multimodal Learning

Yuxing Lu, Xinru Guan, Wei Wu, Li Quan, Lin Wang, Chen Li, Jinzhuo Wang

This paper introduces MetaKG, a metabolite-centric knowledge graph with self-supervised learning that improves representation learning and uncovers biochemical relationships.

bioRxiv · Oct 19, 2026 · PreprintBioinformatics

Neonatal Platelets Differentiate Monocytes to a Myeloid Derived Suppressor Cell Phenotype

Preeti Maurya, Daniel P. O’Reilly, Zachary T. Hilt, Alison C. Livada, Kathleen E. McGrath, Chen Li, Sara K. Ture, Michael W. Malloy, Ei Thanda Tun, James Palis, Craig N. Morrell

This study shows neonatal platelets induce monocytes to a Myeloid Derived Suppressor Cell phenotype, limiting T-cell activation, which may explain adverse outcomes of platelet transfusions in neonates.

Blood · Apr 16, 2026Peer-reviewedImmunology

D-LMBmapX: Generalised Deep Learning Pipeline for 5D Whole-brain Circuitry Profiling

Zhongyu Li, Peiqi Li, Hangzhen Pan, Annabel M.J. Adams, Zuqi Huang, Yaoyu Su, He Liu, Jinjiang Li, Baoming Zhong, Yuqin Su, Liam Bray, Robyn N. Sturgess, Chen Li, Jihua Zhu, Dingwen Zhang, , Jing Ren

D-LMBmapX provides a deep learning pipeline for automated whole-brain circuitry profiling across development, enabling accurate registration and analysis of neural connectivity.

bioRxiv · Feb 25, 2025 · PreprintNeuroscience

Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner.

Zhengping Shao, Brian J. Lee, Hanwen Zhang, Xiaohui Lin, Chen Li, Wenxia Jiang, Napon Chirathivat, Steven Gershik, Michael M. Shen, Richard J. Baer, Shan Zha

This study shows that catalytically inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner, revealing its severe impact on normal tissues.

Proceedings of the National Academy of Sciences · Jul 24, 2023Peer-reviewedGenetics