Molecular BiologybioRxivPreprint
Analysis of crosslinking sites suggests C. elegnas PIWI Argonaute exhibits flexible conformations for target recognition
Wei Wu, Dong-En Lee, Chi-Jung Chung…·Heng-Chi Lee
The paper develops MUTACLASH to analyze CIMs in CLASH data, revealing that CIMs are enriched at piRNA/miRNA target sites and suggest flexible conformations of PRG-1 for target recognition.
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