Pharmacology & ToxicologybioRxivPreprint
The Critical and Unexpected Role of a Methyl Group in Interleukin-17A Inhibitors
Xiaobing Deng, Bo Li, Huiling Chen…·Ye Zhou
The paper investigates the impact of a methyl group substitution in IL-17 inhibitors, finding that replacing a difluoro group with a methyl significantly improves safety and efficacy.
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